Botox Can Affect Brain

Botox can travel to the brain, a new study in rats shows. Botulinum neurotoxin type A – sold commercially under the name Botox, leaves a sign of its presence the remnants of a protein that botulinum breaks down. This is a cause for concern since it is not known at this time how Botulinum affects the brain.
Botox is currently the subject of an FDA investigation because it has been linked to respiratory problems and death in some instances. Botulinum neurotoxin type A – sold commercially under the name Botox – disrupts nerve signalling by targeting SNAP-25, a protein that helps carry neurotransmitters between adjacent nerve cells. It causes botulism, a paralytic illness that can be fatal.
Clinicians had assumed that the powerful poison is safe for use – including for cosmetic purposes – because studies suggest it sits at the site of injection and does not spread through tissue. That may be an assumption too far, however.