Study Suggests Link Between Contraceptive and Bone Loss

The popular, injectable contraceptive known as Depo-Provera has been linked to significant bone loss in women taking the drug. The study shows bone loss in 45% of women taking the contraceptive drug to be as high as 5%. The new study appears in January’s issue of Obstetrics and Gynecology. It’s estimated that more than 2 million women use Depo-Provera including 400,000 teenagers.
At this point, the women most at risk of bone loss are those who use Depo-Provera and smoke and/or don’t receive a sufficient amount of calcium in their diet.
The popular contraceptive depot medroxyprogesterone acetate, better known as DMPA or Depo-Provera is a hormone injection that lasts for 3 months preventing pregnancy. The injection contains synthetic progesterone and no estrogen.
Depo-Provera has carried a black box warning since 2004 concerning potential bone loss in users.