Two Parkinson’s Drugs Linked to Heart Valve Problems

Permax and Dostinex, two drugs used to treat Parkinson’s disease have been linked to serious heart valve damage. Pergolide, sold as Permax, has carried a black box warning from the FDA since 2006. The warning includes the following: ”Some patients have required valve replacement, and deaths have been reported.”
A milder warning was issued for Dostinex just last month.